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Transglutaminase

Host Organism

Streptomyces mobaraensis

Type

Other Ligase

Sequence

MRIRRRALVFATMSAVLCTAGFMPSAGEAAADNGAGEETKSYAETYRLTADDVANINALNESAPAASSAGPSFRAPDSDDRVTPPAEPLDRMPDPYRPSYGRAETVVNNYIRKWQQVYSHRDGRKQQMTEEQREWLSYGCVGVTWVNSGQYPTNRLAFASFDEDRFKNELKNGRPRSGETRAEFEGRVAKESFDEEKGFQRAREVASVMNRALENAHDESAYLDNLKKELANGNDALRNEDARSPFYSALRNTPSFKERNGGNHDPSRMKAVIYSKHFWSGQDRSSSADKRKYGDPDAFRPAPGTGLVDMSRDRNIPRSPTSPGEGFVNFDYGWFGAQTEADADKTVWTHGNHYHAPNGSLGAMHVYESKFRNWSEGYSDFDRGAYVITFIPKSWNTAPDKVKQGWP

External Links

PDB ID: 1IU4
EC: 2.3.2.13
MEROPS: -
UniProt ID: P81453
NCBI: -

Substrate Specificity

-

Functions

  • Catalyzes the cross-linking between Glutamic acid side-chain and an amine

Expression Platform:

  • E.coli

Mutations:

-

Other Properties:

-

References:

  1. [1] (Structure) Kashiwagi, T.; Yokoyama, K.; Ishikawa, K.; Ono, K.; Ejima, D.; Matsui, H.; Suzuki, E. Crystal structure of microbial transglutaminase from Streptoverticillium mobaraense. J Biol Chem 2002, 277 (46), 44252-44260. DOI: 10.1074/jbc.M203933200