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Transglutaminase

Host Organism

Streptococcus suis

Type

Other Ligase

Sequence

MIPIQQHGKRWLILTLTLSTSVLALASIGTSQPVVFADENSHLQSPKNTNKIEVLNWEAFSKKLKDYSSDQRQFHVLKLGFENRLGTLSTREELEEFGKNNNFLVINGKVTQNIHDFPHILVMNKGDVIAHNEEDYHNQMRELRFSGNGDLHNSMEPKRIHALFKIELDSNKRQLLNAAGLGTAENSLKNINGMTIYSHGLTVDNKYYEDYSKYTHNSVKNINVTKERFIANDDLIHKLIESSEAMKQSSERDKVKAFVQYVANHTTYDWEAANKAVQNYADINYYLGSDLFAVTERQKAMCVGFSTTAARAFNMLGLPAYVVVGKNAEGVPHATARVYYDKKWHTIDGTGFITGNKHQRSAKYSEKHFSTIGEDSYDVVEAGQEPKAERNYMIIDSNYESWAMKQKTADLLLFNKEKSLVGLDYIAYVEPTYITENKKNHLLDIYKALKRKVEETKATDKDDKDDKQEGYDRVLQFVNSDIDKLSALSKITEEEFKALENSMDLARVFLGQMNAKAGKEFSEGETYQSYLKNRQKNNTNSDDDRNRNELQENQANSDEVSQNSKDASAPSVNSAQQSEELEGTPSTQETISAAPSQQTPAAPKALQAKTELEDKTETSSLGNTEMVSPSSETAQNTVDSKEESDAKLPYVEPSSKESSEAQVNTVSSPQVSSASPTSSETISTDTVTASQEKAESRVSAPQVISASQTSPETNSAEVVTTSQEVAKAPVSAPQVSSEIQTLSETAPTEVATEAPELSALESNPAPQTSLETTPTEEVTETPEPSVVESNSASPTSPETNSAEAVTTSQEMAEPSVSVPQVSSEIPTSSETAPAEVATEVSEESSSASQPSPETTPTETVTTSQEVAEAPVSAPQVSSEIPTSPETASTEVVVAKQEVADSPVSAPQVISEIPTSSETAPAEVATEVTEPSVVASSSASPTSPEANSTEVVVAKQEVADPLVSAPQTSSASLTLEVPKNEHLDEKADATTPNGVEANTHEAVSVPTSDIRVQDAGSDTVPQPYSLSATLFEEAISTVEPVGVATSSQERSAVAGKVKVPTSLERSNNSVEEEKVVDSNATIENREPEKKEILTSENVLNSLVTIWVALSTSFFMRYFSRGK

External Links

PDB ID: 4XZ7
EC: 2.3.2.13
MEROPS: -
UniProt ID: A5JSJ3
NCBI: -

Substrate Specificity

-

Functions

  • Catalyzes the cross-linking between Glutamic acid side-chain and an amine

Expression Platform:

  • E.coli

Mutations:

-

Other Properties:

-

References:

  1. [1] (Structure) Yu, J.; Pian, Y.; Ge, J.; Guo, J.; Zheng, Y.; Jiang, H.; Hao, H.; Yuan, Y.; Jiang, Y.; Yang, M. Functional and Structural Characterization of the Antiphagocytic Properties of a Novel Transglutaminase from Streptococcus suis. Journal of Biological Chemistry 2015, 290 (31), 19081-19092. DOI: https://doi.org/10.1074/jbc.M115.643338